Abstract: This paper takes the chemical reagent temporary storage room (intermediate storage) of biomedical laboratory as the research object,discusses the compliance of chemical reagent temporary storage room,technical prevention measures,safety management system construction,emergency management,and the use of CRW software to assist the evaluation of hazardous chemicals storage contraindications. The research content has practical reference value for understanding and optimizing the safety management of chemical reagent storage rooms in college and university laboratories,and provides some ideas and methods for the safety management of college and university laboratories.