Abstract: Criminal Science and Technology majors are nurtured to serve as innovative,skilled professionals for the public security system,where chemistry-focused courses,particularly hands-on lab work,form the curriculum's core.This paper investigates the integration of a problem-oriented flipped classroom model into chemical experimental teaching,utilizing blood ethanol analysis through headspace gas chromatography as a study.Through careful resource preparation,fostering autonomous learning,well-structured assessments,and active classroom interaction,our teaching approach strives to cultivate students'intrinsic motivation for learning,experimental curiosity,innovative thought processes,and research acumen.This pedagogical shift is not only aligned with current academic progression but is crucial for grooming the required talents within the Criminal Science and Technology field to meet modem societal needs.