Abstract: Tilatamine is mainly used for anesthesia in pets and small animals. Clinically, it is also used as an induction anesthetic or in combination with other anesthetic drugs to enhance the anesthetic effect. In recent years, tilatamine has gradually come into the public eye. Due to its similar chemical structure to the drug ketamine (K powder) and the similar reactions it causes in the human body, it has been used by lawbreakers as a substitute for new types of drugs, especially illegally added and sold in electronic cigarettes, which has attracted widespread social attention.